Ruslan Dmitriev
Ghent University, Belgium
Education
2008 – Ph.D. (Bioorganic Chemistry, 23.05.2008), Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
2004 – M.Sc. (Chemistry, with distinction), Moscow State Academy of Fine Chemical Technology, Moscow, Russia.
Employment
2020-present – Assistant Professor, Head of Tissue Engineering and Biomaterials Group, Ghent University, Ghent, Belgium (FTE 100%)
2018-2020 – Research Fellow, University College Cork, Cork, Ireland
2014-2018 – Starting Investigator / Research Fellow, University College Cork, Cork, Ireland
2014-2014 – Senior Postdoctoral Researcher, Irish Photonics Integration Centre I-PIC, University College Cork, Ireland
2013-2014 – Principal Investigator on Science Foundation Ireland Technical Innovation Development Award grant, University College Cork, Cork, Ireland
2008-2012 – Postdoctoral Researcher, University College Cork, Cork, Ireland
Other experience
2019 – research & training on two-photon FLIM-PLIM at the Laboratory of Prof. K. Schenke-Layland (University of Tübingen, Germany)
2018-2020 – Chief researcher (part-time), Institute for Regenerative Medicine, Sechenov University, Russian Federation (FTE 10%)
Teaching responsibilities
2024 – FEBS Course on Functional imaging of cellular dynamics (9-15 June 2024, University of Amsterdam, AVL, June-2024, instructor)
2020-present – teaching M.Sc. courses in biomedical science and engineering (Ghent University, 6 in total), Tissue engineering (D001923, D012692), Biomaterials and Tissue engineering (D012251, E063671). Lecturer in charge, co-lecturer and responsible for Major in Tissue Engineering & Regenerative Medicine MSc program.
2020-present – Invited lecturer at Trinity College Dublin for M.Sc. course (Advanced Medical Imaging, 5Bio7)
2020-2020 – Part-time lecturer (University College Cork, BC4017; Biosensors & Tissue engineering)
2012-2017 – Instructor (co-lecturer) on postgraduate teaching module at University College Cork, BC6001 ‘Molecular and Cell Biology’ (delivering lectures, preparing and assessing exams, coordinating the course content)
Awards
Won 13 travel grants to attend the international conferences: American Society of Biochemistry and Molecular Biology (ASBMB) graduate student and postdoctoral travel awards for Experimental Biology symposia (USA; 2007, 2011, 2012, 2014, 2015), American Society for Cell Biology (ASCB) postdoctoral travel award for Annual Meeting (USA; 2011, 2017, 2019, 2022), Biophysical Society (USA; 2020), Society of General Physiologists (USA; 2005) and Research Foundation Flanders FWO (2022, 2023).
2024 – Early Career Investigator award (Histochemical Society)
Imaging oxygenation and metabolism in organoids using FLIM and PLIM
Speaker: Ruslan I. Dmitriev, PhD, Assistant Professor
1Tissue Engineering and Biomaterials Group, Ghent University, Ghent, Belgium
2Ghent Light Microscopy Core (GLiM), Ghent University, Ghent, Belgium
Success in engineering of organoids, spheroids and related 3D microtissues is often hampered by their intrinsic heterogeneity and dynamic gradients of biomolecules. Live changes of cell metabolism, mitochondrial activity, physical characteristics and O2 are hard to predict and control without dynamic microscopy approaches. My group addresses the challenge of non-destructive quantitative multi-parametric imaging of 3D tissue models by using high-performance nanosensors, small molecule conjugates and live fluorescence (FLIM) and phosphorescence (PLIM) lifetime imaging microscopies. In my talk I will discuss how the imaging of autofluorescence, hypoxia, and other (bio)markers can be performed in stem cell-derived small intestinal organoids. I will discuss how “FLIM of organoids” methodology can address the emerging biomedical problem of the micro- and nanoplastic pollution.